Hypoparathyroidism affects less than 5 in 10,000 people in the European Union (EU) or approximately 257,000 individuals. In the United States (US) The prevalence of hypoparathyroidism is estimated to be 37 per 100,000, with 78% of cases caused by surgery, 7% due to genetic disorder and 6% due to idiopathic origin. Although incidence rates have been difficult to quantify, it is estimated that chronic hypoparathyroidism, which affects patients for more than six months, affects approximately 58,700 insured individuals in the United States, with an estimated 43% of these chronic cases characterized as mild, 39% characterized as moderate, and 18% characterized as severe.