In the U.S there are approximately seven million new fractures/broken bones each year, with approximately 300,000 developing slowly (delayed union) or nonunion fractures. Estimates for the average non-union treatment cost vary from nearly $25,000 to $45,000. Nonunions are estimated to cost the health care system in the US $9.2 billion/ year. The estimated addressable market for nonunion and enhanced healing of fractures for the EU is approximately 0.7 to 2 billion Euros per year, assuming an expense of approximately 2,000 to 2,500 Euro per treatment regimen. These estimates exclude losses in productivity to the economy.

Bone HealingFotolia